Scientists around the world are working hard to come up with a COVID-19 vaccine to suppress the pandemic. How can the EU guarantee that rapidly approved vaccines are safe and effective? We asked senior representatives from the European Medicines Agency (EMA) and the European Centre for Disease Prevention and Control (ECDC) for their thoughts.
Patients with severe COVID-19 pneumonia often need to be mechanically intubated and have an increased mortality risk. Tocilizumab, a drug used against the cytokine storm underlying this clinical condition, has shown positive effects in clinical trials.
A few weeks after the SARS-CoV-2 was identified by Chinese researchers as the cause of ‘COVID-19’, an antiviral called remdesivir, originally used during the 2014 Ebola outbreak, came into play as the first available option to treat patients with coronavirus disease 2019 (COVID-19). Even if the approval process for remdesivir caused some controversy, experts consider the combined use of antivirals and other drugs a promising solution for treatment of Covid-19.
Interview with Peter Piot, Director of the London School of Hygiene and Tropical Medicine and Special Advisor to the President of the European Commission on the response to the coronavirus and COVID-19: how science has been feeding into policy-making? What does your role as EU special advisor on COVID-19 entail? I am part of the ...
So far, sending children back to school does not seem to have increased community transmission rates, even though EU countries have adopted different strategies. Keeping schools open is very important for children’s health and well-being.
Clinical trials make it possible to evaluate whether a treatment improves outcomes. Developing a hypothesis, for example if treatment A is better than standard treatment B, clinical trials enable understanding of the role of an intervention in improving patient care. In the current search for a successful treatment against COVID-19, ongoing multiple clinical trials have started to make a difference, such as the Recovery clinical trial on dexamethasone, which has given a definitive verdict on the use of corticosteroids during COVID-19.
With many countries around the world beginning to see or anticipating a resurgence of COVID-19, attention has been turning to how to avoid an economically punishing second round of lockdowns while keeping transmission down. One method is by examining the types of hotspots where clusters of cases emerge.
The COVID-19 pandemic brought about worldwide disruption. As societies tentatively begin to reopen, the pandemic holds lessons for how the world faces another globally existential threat, the climate crisis.
“Test, test, test” was one of the mantras of the World Health Organization (WHO) director general Tedros Adhanom Ghebreyesus. The issue is particularly relevant in the “unlocking” phase several European countries are going through, as the curve of the pandemics bends. At this stage, and while effective vaccines or therapies are still not available, tests are crucial to keep the disease at bay. But are they effective and reliable?